LINEAS DE INVESTIGACIÓN

ORGANISMOS FINANCIADORES ÚLTIMOS 5 AÑOS

PUBLICACIONES ÚLTIMOS 5 AÑOS

-Martínez-López, J.; Márquez, A.; Pegoraro, F.; Ortiz-Fernández, L.; Acosta-Herrera, M.; Kerick, M.; Gelain, E.; Diamond, E.L.; Durham, B.H.; Abdel-Wahab, O.; Go, R.S.; Koster, M.J.; Dagna, L.; Campochiaro, C.; Collin, M.; Milne, P.; Estrada-Veras, J.I.; O'Brien, K.; Papo, M.; Cohen-Aubar, F.; Amoura, Z.; Haroche, J.; Martín, J.; Vaglio, A., Genome-Wide Association Study Identifies the First Germline Genetic Variant Associated With Erdheim-Chester Disease, Arthritis and Rheumatology, 2024, Vol. 76: 141-145, ARTÍCULO, Id:971544

-Inmaculada Rodriguez-Martin; Gonzalo Villanueva-Martin; Alfredo Guillen-Del-Castillo; Norberto Ortego-Centeno; José L Callejas; Carmen P Simeón-Aznar; Javier Martin; Marialbert Acosta-Herrera, Contribution of Telomere Length to Systemic Sclerosis Onset: A Mendelian Randomization Study, International Journal of Molecular Sciences, 2023, Vol. 24: 1558921-15589, ARTÍCULO, Id:955844

-Masahiro Kanai; Javier Martin; Marialbert acosta; Matthew Solomonson; Jordi Pérez-Tur, A second update on mapping the human genetic architecture of COVID-19, Nature, 2023, Vol. 621: E7-E26, ARTÍCULO, Id:955804

-Gonzalo Villanueva-Martin; Marialbert Acosta-Herrera; Elio G Carmona; Martin Kerick; Norberto Ortego-Centeno; Jose Luis Callejas-Rubio; Norbert Mages; Sven Klages; Stefan Börno; Bernd Timmermann; Lara Bossini-Castillo; Javier Martin, Non-classical circulating monocytes expressing high levels of microsomal prostaglandin E2 synthase-1 tag an aberrant IFN-response in systemic sclerosis, Journal of Autoimmunity, 2023, Vol. 140: 103097-103097, ARTÍCULO, Id:953970

-Martínez-López, J.; Kerick, M.; Ortiz-Fernández, L.; Acosta-Herrera, M.; Márquez, A.; Martín, J., FLT3 functional low-frequency variant rs76428106-C is associated with susceptibility to systemic sclerosis, Rheumatology, 2023, Vol. 62: SI138-SI142, ARTÍCULO, Id:941877

-Martin Kerick; Marialbert Acosta-Herrera; Carmen Pilar Simeón-Aznar; José Luis Callejas; Shervin Assassi; International SSc Group; Susanna M Proudman; Mandana Nikpour; Australian Scleroderma Interest Group (ASIG); PRECISESADS Clinical Consortium; Nicolas Hunzelmann; Gianluca Moroncini; Jeska K de Vries-Bouwstra; Gisela Orozco; Anne Barton; Ariane L Herrick; Chikashi Terao; Yannick Allanore; Carmen Fonseca; Marta Eugenia Alarcón-Riquelme; Timothy R D J Radstake; Lorenzo Beretta; Christopher P Denton; Maureen D Mayes; Javier Martin, Complement component C4 structural variation and quantitative traits contribute to sex-biased vulnerability in systemic sclerosis, npj Genomic Medicine, 2022, Vol. 7: 571-57, ARTÍCULO, Id:905423

-Gonzalo Villanueva-Martin; Marialbert Acosta-Herrera; Martin Kerick; Elena Lopez-Isac; Carmen Pilar Simeon; Yannick; Allanore; Susanna M. Proudman; Mandana Nikpour; Carmen Fonseca; Christopher P. Denton; Timothy R. D. J. Radstake; Mayes D Maureen; Xia Jiang; Javier Martín; Lara Bossini-Castillo, The effect of body fat distribution on systemic sclerosis, Journal of Clinical Medicine, 2022, Vol. 11: 60120-6014, ARTÍCULO, Id:905418

-Casares-Marfil D; Guillen-Guio B; Lorenzo-Salazar JM; Rodríguez-Pérez H; Kerick M; Jaimes-Campos MA; Díaz ML; Estupiñán E; Echeverría LE; González CI; Martin J*; Flores C*; Acosta-Herrera M*., Admixture mapping analysis reveals differential genetic ancestry associated with Chagas disease susceptibility in the Colombian population., Human Molecular Genetics, 2021, Vol. 30: 2503-2512, ARTÍCULO, Id:861246

-Desiré Casares-Marfil; Martin Kerick; Eduardo Andrés-León; Pau Bosch-Nicolau; Israel Molina; Chagas Genetics CYTED Network; Javier Martin; Marialbert Acosta-Herrera, GWAS loci associated with Chagas cardiomyopathy influences DNA methylation levels, PLoS Neglected Tropical Diseases, 2021, Vol. 15: 9874-e0009874, ARTÍCULO, Id:856180

-Acosta-Herrera M; Kerick M; Lopéz-Isac E; Assassi S; Beretta L; Simeón-Aznar CP; Ortego-Centeno N; International SSc Group; Proudman SM; Australian Scleroderma Interest Group (ASIG; Hunzelmann N; Moroncini G; de Vries-Bouwstra JK; Orozco G; Barton A; Herrick AL; Terao C; Allanore Y; Brown MA; Radstake TR; Fonseca C; Denton CP; Mayes MD; Martin J., Comprehensive analysis of the major histocompatibility complex in systemic sclerosis identifies differential HLA associations by clinical and serological subtypes., Annals of the Rheumatic Diseases, 2021, Vol. 80: 1040-1047, ARTÍCULO, Id:845388

-Casares-Marfil D; Strauss M; Bosch-Nicolau P; Lo Presti MS, Molina I; Chevillard C; Cunha-Neto E; Sabino E; Ribeiro AL; González CI; Martín J*; Acosta-Herrera M*., A genome-wide association study identifies novel susceptibility loci in chronic Chagas cardiomyopathy, Clinical Infectious Diseases, 2021, Vol. 73: 672-679, ARTÍCULO, Id:845384

-Kerick M; González-Serna D; Carnero-Montoro E; Teruel M; Acosta-Herrera M; Makowska Z; Buttgereit A; Babaei S; Barturen G; López-Isac E; PRECISESADS Clinical Consortium; Lesche R; Beretta L; Alarcon-Riquelme ME; Martin J, Expression Quantitative Trait Locus Analysis in Systemic Sclerosis Identifies New Candidate Genes Associated With Multiple Aspects of Disease Pathology, Arthritis and Rheumatology, 2021, Vol. 73: 1288-1300, ARTÍCULO, Id:845257

-Natalia Hernandez-Pacheco; Mario Gorenjak; Sta?a Jurgec; Almudena Corrales; Andrea Jorgensen; Leila Karimi; Susanne J Vijverberg; Vojko Berce; Maximilian Schieck; Marialbert Acosta-Herrera; Martin Kerick; Lesly-Anne Samedy-Bates; Roger Tavendale; Jesús Villar; Somnath Mukhopadhyay; Munir Pirmohamed; Katia M C Verhamme; Michael Kabesch; Daniel B Hawcutt; Steve Turner; Colin N Palmer; Esteban G Burchard; Anke H Maitland-van der Zee; Carlos Flores; Uro? Poto¿nik; Maria Pino-Yanes; PiCA and SysPharmPedia consortia, Combined analysis of transcriptomic and genetic data for the identification of loci involved in glucocorticosteroid response in asthma, Allergy: European Journal of Allergy and Clinical Immunology, 2021, Vol. 76: 1238-1243, CARTA AL EDITOR, Id:842146

-Cristina Regueiro; Desire Casares-Marfil; Karin Lundberg; Rachel Knevel; Marialbert Acosta-Herrera; Luis Rodriguez-Rodriguez; Raquel Lopez-Mejias; Eva Perez-Pampin; Ana Triguero-Martinez; Laura Nuño; Ivan Ferraz-Amaro; Javier Rodriguez- Carrio; Rosario Lopez-Pedrera; Montse Robustillo-Villarino; Santos Castañeda; Sara Remuzgo-Martinez; Mercedes Alperi; Juan J Alegre-Sancho; Alejandro Balsa; Isidoro Gonzalez-Alvaro; Antonio Mera; Benjamin Fernandez-Gutierrez; Miguel A Gonzalez-Gay; Leendert A Trouw; Caroline Grönwall; Leonid Padyukov; Javier Martin; Antonio Gonzalez, HLA-B*08 identified as the most associated MHC locus for anti-carbamylated protein antibody-positive/anti-CCP-negative rheumatoid arthritis, Arthritis and Rheumatology, 2021, Vol. 73: 963-969, ARTÍCULO, Id:842142

-Guillermo Barturen; Sepideh Babaei; Francesc Català-Moll; Manuel Martínez-Bueno; Zuzanna Makowska; Jordi Martorell-Marugán; Pedro Carmona-Sáez; Daniel Toro-Domínguez; Elena Carnero-Montoro; María Terue; Martin Kerick; Marialbert Acosta-Herrera; Lucas Le Lann; Christophe Jamin; Javier Rodríguez-Ubreva; Antonio García-Gómez; Jorge Kageyama; Anne Buttgereit; Sikander Hayat; Joerg Mueller; Ralf Lesche; Maria Hernandez-Fuentes; Maria Juarez; Tania Rowley; Rosario Lopez-Pedrera; Rafaela Ortega-Castro; Norberto Ortego; Enrique Raya; Carolina Artusi; Robert J Benschop; Chris Chamberlain; Ernst R Dow; Yiannis Ioannou; Laurence Laigle; Jacqueline Marovac; Jerome Wojcik; Yves Renaudineau; Maria Orietta Borghi; Johan Frostegård; Javier Martín; Lorenzo Beretta; Esteban Ballestar; Fiona McDonald; Jacques-Olivier Pers; Marta E Alarcón-Riquelme, Integrative Analysis Reveals a Molecular Stratification of Systemic Autoimmune Diseases, Arthritis and Rheumatology, 2021, Vol. 73: 1073-1085, ARTÍCULO, Id:842140

-Lara Bossini-Castillo;  Gonzalo Villanueva-Martin; Martin Kerick; Marialbert Acosta-Herrera; Elena López-Isac; Carmen P Simeón; Norberto Ortego-Centeno; Shervin Assassi; International SSc Group;  Australian Scleroderma Interest Group (ASIG);  PRECISESADS Clinical Consortium;  PRECISESADS Flow Cytometry study group;  Nicolas Hunzelmann; Armando Gabrielli; J K de Vries-Bouwstra; Yannick Allanore; Carmen Fonseca; Christopher P Denton; Timothy Rdj Radstake; Marta Eugenia Alarcón-Riquelme; Lorenzo Beretta; Maureen D Mayes; Javier Martin, Genomic Risk Score impact on susceptibility to systemic sclerosis, Annals of the Rheumatic Diseases, 2021, Vol. 80: 118-127, ARTÍCULO, Id:818450

-David González-Serna; Gonzalo Villanueva-Martin; Marialbert Acosta-Herrera; Ana Márquez; Javier Martín, Approaching Shared Pathophysiology in Immune-Mediated Diseases through Functional Genomics, GENES, 2020, Vol. 11: 148212-1482, ARTÍCULO, Id:818500

-Strauss, M.; Casares-Marfil, D.; Alcaraz, A.; Palma-Vega, M.; Bosch-Nicolau, P.; Lo Presti, M.S.; Molina, I.; González, C.I.; Martín, J.; Acosta-Herrera, M., Lack of Association of IL6 polymorphism with the susceptibility to Chagas disease in Latin American populations, Acta Tropica, 2020, Vol. 210: 105546, ARTÍCULO, Id:809482

-Strauss, M.; Palma-Vega, M.; Casares-Marfil, D.; Bosch-Nicolau, P.; Lo Presti, M.S.; Molina, I.; González, C.I.; Paglini, P.A.; Schijman, A.G.; Robello, C.; Echeverría, L.E.; Vargas-Alarcón, G.; Calzada, J.E.; Fernández-Mestre, M.; Fresno, M.; Pinazo, M.J.; Martín, J.; Acosta-Herrera, M., Genetic polymorphisms of IL17A associated with Chagas disease: results from a meta-analysis in Latin American populations, Scientific Reports, 2020, Vol. 10: 1-5015, ARTÍCULO, Id:805792

-Casares-Marfil, D.; Martín, J.; Acosta-Herrera, M., Genomic opportunities for drug repositioning in systemic seropositive rheumatic diseases, Expert Review of Clinical Immunology, 2020, Vol. 16: 343-346, EDITORIAL, Id:805532

TESIS DOCTORALES ÚLTIMOS 5 AÑOS