SUMMARY OF RESEARCH
Development of methodologies for cytosolic protein delivery.
1. Garcia, J.; Fernández-Pradas, M.; Lladó, A.; Serra, P.; Zalvidea, D.; Kogan, M.J.; Giralt, E.*; Sánchez-Navarro, M.* The combined use of gold nanoparticles and infrared radiation enables cytosolic protein delivery, Chemistry: a European Journal, 2021, in press. DOI: 10.1002/chem.202005000.
2. Sánchez-Navarro, M.* Peptide-mediated cytosolic protein delivery Advanced Drug Delivery Reviews, 2021,171, 187-198.
3. Sánchez-Navarro; M.; Teixidó, M.; Giralt., E. Cytosolic delivery: Just passing through. Nature Chemistry. 2018 9 - 8, 727 - 728.
Development of BBB-shuttle peptides.
1. Díaz-Perlas, C.; Varese, M.; Guardiola, S.; García, J.; Sánchez-Navarro, M.; Giralt, E.; Teixidó, M. From venoms to BBB-shuttles. MiniCTX3: a molecular vector derived from scorpion venom. Chemical communications 2018, 54, 12738-12741.
2. Oller-Salvia, B.; Sánchez-Navarro, M.; Ciudad, S.; Guiu, M.; Arranz-Gibert, P.; Garcia, C.; Gomis, R.; Cecchelli, R.; García, J.; Giralt, E.; Teixidó, M. Miniap-4: A Venom-Inspired Peptidomimetic for Brain Delivery Angewandte Chemie - International Edition, 2016, 55 572.
3. Díaz-Perlas C; Oller-Salvia, B.; Sánchez-Navarro, M.*, Teixidó, M.*; Giralt, E.*. Branched BBB-shuttle peptides: chemoselective modification of proteins to enhance blood-brain barrier transport Chemical Science. 2018, 9, 8409-8415
4. Sánchez-Navarro; M.; Teixidó, M.; Giralt., E. Jumping Hurdles: Peptides Able To Overcome Biological Barriers. Accounts of Chemical Research. 2017, 50, 1847 - 1854.
5. Sánchez-Navarro; M.; Giralt., E.; Teixidó, M. Blood-brain barrier peptide shuttles. Current Opinion in Chemical Biology. 2017, 38, 134 - 140.
6. Oller-Salvia, B., Sánchez-Navarro, M., Giralt, E., Teixidó, M. Blood-brain barrier shuttle peptides: an emerging paradigm for brain delivery, Chemical Society Reviews, 2016, 45, 4690-4707.
7. Bukchin, A.; Sánchez-Navarro, M.; Carrera, A.; Resa-Pares, C.; Castillo-Ecija, H.; Balaguer-Lluna, L.; Teixidó, M.; Olaciregui, N. G.; Giralt, E.; Carcaboso, A. M.; Sosnik, A. Amphiphilic Polymeric Nanoparticles Modified with a Protease-Resistant Peptide Shuttle for the Delivery of SN-38 in Diffuse Intrinsic Pontine Glioma ACS Applied Nano Materials, 2021, in press. DOI: 10.1021/acsanm.0c02888.
8. Bukchin, A.; Sánchez-Navarro, M.; Carrera, A.; Teixidó, M.; Carcaboso, A.; Giralt, E.; Sosnik, A. Amphiphilic Polymeric Nanoparticles Modified with a Retro-Enantio Peptide Shuttle Target the Brain of Mice. Chemistry of Materials, 2020, 32(18) 7679-7693.
Development of intestinal permeation enhancers.
1. Garcia, J. Fernández-Blanco, A.; Teixidó, M.; Sánchez-Navarro, M.*, Giralt, E.* D-Polyarginine Lipopeptides as Intestinal Permeation Enhancers ChemMedChem, 2018, 13, 2045-2052.
2. Sánchez-Navarro, M.; Garcia, J.; Giralt, E.; Teixidó, M. Using peptides to increase transport across the intestinal barrier Advanced Drug Delivery Reviews, 2016, 106, 355-366.
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